Successful Treatment with Caspofungin of Hepatosplenic Candidiasis Resistant to Liposomal Amphotericin B
نویسندگان
چکیده
منابع مشابه
Successful treatment with caspofungin of hepatosplenic candidiasis resistant to liposomal amphotericin B.
Sir—In their study of the community prevalence of carriage of methicillin-resistant Staphylococcus aureus (MRSA) among San Francisco's urban poor, Charlebois et al. [1] found an overall prevalence of MRSA carriage of 2.8%. Injection drug use and prior hospitalization within 1 year were significant multivariate risk factors for MRSA acquisition. During the spring of 2000, a similar point prevale...
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Genera of the order Mucorales (Rhizopus, Mucor, Rhizomucor, Absidia, Apophysomyces, Cunninghamella, and Saksenaea) cause an angioinvasive infection called zygomycosis. Mortality rates can approach 100% depending on the patient's underlying disease and form of zygomycosis. We report here on the unusual case of a patient with acute myelogenous leukemia and zygomycosis unresponsive to monotherapy ...
متن کاملTreatment of neonatal candidiasis with liposomal amphotericin B.
A liposomal amphotericin B preparation (L-AMP-LRC-1) has been developed and tested successfully in adults by us. This preparation was administered to 23 neonates with candidiasis in an open phase II study. All the 14 assessable patients responded completely to the L-AMP-LRC-1 therapy given at 1 mg/kg for 28 days. Compared to AmBisome, another liposomal formulation of amphotericin B, L-AMP-LRC-1...
متن کاملHepatosplenic candidiasis: successful treatment with fluconazole.
PURPOSE To determine if fluconazole is effective treatment for hepatosplenic candidiasis that has not resolved with amphotericin B and flucytosine treatment. PATIENTS AND METHODS Six patients (ages 3 to 44) with acute leukemia and hepatosplenic candidiasis who did not respond to prior antifungal therapy were treated with fluconazole. RESULTS All six patients had fever and three had nausea a...
متن کاملSuccessful initial treatment with caspofungin alone for hepatosplenic candidiasis in a patient with acute myeloblastic leukemia.
C disseminated candidiasis or Hepatosplenic candidiasis (HSC) is a rare and potentially morbid and mortal complication encountered in febrile neutropenic patients. It is generally associated with recovery from neutropenia, and may occur after the treatment of an episode of acute hematogenous candidiasis. Clinical signs and symptoms include fever unresponsive to antibiotics, abdominal pain and t...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2002
ISSN: 1058-4838,1537-6591
DOI: 10.1086/343748